GHR Polyclonal Antibody (E-AB-17322)
For research use only.
| Verified Samples |
Verified Samples in WB: Raji, K562, SKOV3, PC-3 |
| Dilution | WB 1:500-2000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GHR |
| Abbre | GHR |
| Synonyms | GH receptor, GH-binding protein, GHBP, GHR, Growth hormone binding protein, Growth hormone receptor, Growth hormone receptor precursor, Growth hormone-binding protein, Increased responsiveness to growth ho, included |
| Swissprot | |
| Calculated MW | 72 kDa |
| Cellular Localization | Secreted, Cell membrane, On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway and Cell membrane, Remains fixed to the cell membrane and is not internalized. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology, Developmental biology, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone.Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth.Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. |
Other Clones
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Other Formats
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Unconjugated
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