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For research use only.

Verified Samples Verified Samples in IHC: Human tonsil, Human brain cerebellum
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human GJB6
Abbre GJB6
Synonyms CXB6,  Connexin 30,  Connexin-30,  Cx30,  DFNA3,  DFNA3B,  DFNB1B,  ECTD2,  ED2,  EDH,  Gap junct,  Gap junction beta 6 protein,  Gap junction beta-6 protein,  beta 6,  beta 6 (connexin 30),  ectodermal dysplasia 2,  gap junction protein,  hidrotic (Clouston syndrome)
Swissprot
Cellular Localization Cell membrane. Cell junction>gap junction.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Neuroscience,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.
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Unconjugated

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