Glypican-3 Monoclonal Antibody (ELAB6929-M)
For research use only.
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | Glypican-3 |
| Cellular Localization | Cytoplasm |
| Tissue Specificity | Liver cancer |
| Storage | The concentrated should be stored at -20°C protecting from light,Valid for 12 months. |
| Shipping | Ice bag |
| background | Glypican 3, a heparan sulfate glycoprotein and oncoembryonic protein, is expressed in the syncytiotrophoblast layer of embryonic liver and placental tissue. GPC-3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor. Studies have shown that GPC-3 protein is expressed in the majority of hepatocellular carcinomas (HCCS) but not in normal liver or benign liver lesions, including dysplastic and cirrhotic nodules. GPC-3 is a sensitive diagnostic marker for hepatocellular carcinoma and a tool to distinguish hepatocellular carcinoma from non-neoplastic liver disease and preneoplastic liver disease. |
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