GNE Polyclonal Antibody (E-AB-63016)

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All	Size	Price	Qty
	200μL	$ 530.00
	120μL	$ 320.00
	60μL	$ 200.00

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Verified Samples	Verified Samples in IHC: Mouse brain, Human esophagus
Dilution	IHC 1:50-1:100
Isotype	IgG
Host	Rabbit
Reactivity	Human, Mouse, Rat
Applications	IHC
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human GNE (NP_001121699.1).
Abbre	GNE
Synonyms	DMRV, GLCNE, GNE, IBM2, NM, Uae1
Swissprot	Q9Y223
Cellular Localization	Cytoplasm.
Concentration	1 mg/mL
Buffer	Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method	Affinity purification
Research Areas	Cardiovascular, Developmental Biology
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background	The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.

Cat.No.	Product Name	Sizes
E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500μL , 120μL , 1mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50mL , 18mL , 6mL , 3mL
E-IR-R220	Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50Assays

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Unconjugated