GPM6A Polyclonal Antibody (E-AB-14718)
For research use only.
Verified Samples |
Verified Samples in WB: Human brain Verified Samples in IHC: Human brain, Human thyroid cancer |
Dilution | WB 1:1000-1:5000, IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human GPM6A |
Abbre | GPM6A |
Synonyms | GPM6A, M6a, Neuronal membrane glycoprotein M6-a |
Swissprot | |
Calculated MW | 31 kDa |
Cellular Localization | Membrane. |
Concentration | 0.4 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene.Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells.Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation.GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways.May be involved in neuronal NGF-dependent Ca2+ influx.May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. |
Other Clones
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Other Formats
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Unconjugated
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