For research use only.
Verified Samples |
Verified Samples in IHC: Human tonsil |
Dilution | IHC 1:30-1:150 |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human GPSM2 |
Abbre | GPSM2 |
Synonyms | DFNB82, G protein signalling modulator 2, G protein signalling modulator 2 (AGS3 like C. elegans), G-protein-signaling modulator 2, GPSM2, Gpsm2, HGNC:29501, LGN, LGN protein, Mosaic protein LGN, Pins |
Swissprot | |
Cellular Localization | Cytoplasm. Cytoplasm>cell cortex. Localizes in the cytoplasm in the interphase and at cell periphery in the metaphase. |
Concentration | 1.92 mg/mL |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Cell Biology, Signal transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses.The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange.This protein may play a role in neuroblast division and in the development of normal hearing.Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).Alternative splicing results in multiple transcript variants. |
Other Clones
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Unconjugated
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