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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human ovarian cancer
Dilution IHC 1:25-1:100
Isotype Rabbit IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human GRIN1
Abbre GRIN1
Synonyms GluN1,  Glutamate [NMDA] receptor subunit zeta-1,  Glutamate receptor ionotropic,  Glutamate receptor ionotropic N methyl D aspartate 1,  Grin1,  MRD8,  N methyl D aspar,  N methyl D aspartate receptor,  N-methyl-D aspartate,  NMDA 1,  subunit 1
Swissprot
Cellular Localization Cell membrane. Cell junction>synapse>postsynaptic cell membrane. Cell junction>synapse>postsynaptic cell membrane>postsynaptic density. Enriched in post-synaptic plasma membrane and post-synaptic densities.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
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