GRK2 Polyclonal Antibody (E-AB-15703)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer |
| Dilution | IHC 1:100-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ADRBK1 |
| Abbre | ADRBK1 |
| Synonyms | ADRBK1, ARBK1, Adrenergic beta receptor kinase 1, BARK, BARK1, Beta ARK 1, Beta ARK1, Beta adrenergic receptor kinase 1, Beta-ARK-1, Beta-adrenergic receptor kinase 1, FLJ16718, G protein coupled receptor kinase 2, G-protein coupled receptor kinase 2, GRK2 |
| Swissprot | |
| Cellular Localization | Cytosol, Plasma Membrane, Other locations: cilium, cytoplasm, membrane. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. |
Other Clones
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Other Formats
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Unconjugated
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