For research use only.
| Verified Samples |
Verified Samples in IHC: Human cervical cancer |
| Dilution | IHC 1:30-1:150 |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human GSKIP |
| Abbre | GSKIP |
| Synonyms | C14ORF129, Chromosome 14 open reading frame 129 , GSK3-beta interaction protein, GSK3beta interaction protein, GSKIP, MGC4945, UPF0279 |
| Swissprot | |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.78 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. |
Other Clones
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