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For research use only.

Verified Samples Verified Samples in WB: Jurkat, Hela, A549
Verified Samples in IHC: Human cervical cancer, Human ovarian cancer
Dilution WB 1:1000-1:5000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human GSR
Abbre GSR
Synonyms GLR1,  GLUR,  GR,  GRD 1,  GRD1,  GRase,  GSHR,  GSR,  Glutathione reductase,  Glutathione reductase mitochondrial,  Gr1,  MGC78522,  mitochondrial
Swissprot
Calculated MW 56 kDa
Cellular Localization Cytoplasm and Mitochondrion.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Other Clones

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Unconjugated

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