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For research use only.

Verified Samples Verified Samples in WB: Human testis, HepG2
Verified Samples in IHC: Human colon cancer, Human liver cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human GSTA3
Abbre GSTA3
Synonyms Glutathione S alkyltransferase A3,  Glutathione S aralkyltransferase A3,  Glutathione S aryltransferase A3,  Glutathione S transfe,  Glutathione S transferase A3,  Glutathione S transferase A3 3,  Glutathione S transferase alpha 3,  glutathione S transferase A3 subunit
Swissprot
Calculated MW 25 kDa
Cellular Localization Cytoplasm.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds.At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6.Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity.However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity.
Other Clones

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Unconjugated

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