GSTM2 Polyclonal Antibody (E-AB-18062)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human lung cancer, Human esophagus cancer |
| Dilution | IHC 1:50-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GSTM2 |
| Abbre | GSTM2 |
| Synonyms | Glutathione S alkyltransferase M2, Glutathione S aralkyltransferase M2, Glutathione S aryltransferase M2, Glutathione S tra, Glutathione S transferase 4, Glutathione S transferase M1, Glutathione S transferase M2 (muscle), Glutathione S transferase Mu 2 (muscle) |
| Swissprot | |
| Cellular Localization | Cytoplasm. |
| Concentration | 1.44 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. |
Other Clones
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Other Formats
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Unconjugated
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