H3F3B Polyclonal Antibody (E-AB-52806)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human cervical cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human H3F3B |
| Abbre | H3F3B |
| Synonyms | H3 histone, H3 histone family 3A, H3 histone family 3B, H3.3, H3.3A, H3.3B, H33, H3F3, H3F3A, H3f3b, Histone H3.3, Histone H3.3Q, Histone H3.A, Histone H3.B, MGC87782, MGC87783, family 3B (H3.3B) |
| Swissprot | |
| Cellular Localization | Nucleus. Chromosome. |
| Concentration | 0.72 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
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