HCN2 Polyclonal Antibody (E-AB-15709)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human breast cancer, Human ovarian cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human HCN2 |
| Abbre | HCN2 |
| Synonyms | BCNG-2, BCNG2, Brain cyclic nucleotide gated channel 2, Brain cyclic nucleotide-gated channel 2, HAC1, HCN2, Hcn2, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cardiovascular, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain. Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages. |
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