HCRT Polyclonal Antibody (E-AB-53517)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human colorectal cancer, Human tonsil |
| Dilution | IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human HCRT |
| Abbre | HCRT |
| Synonyms | HCRT, HCRT1, HCRT2, Hypocretin 1, Hypocretin 2, NRCLP1, OX, Orexin, Orexin A, Orexin B, Orexin precursor, PPORX, PPOX, PREPROOREXIN, hypocretin, hypocretin (orexin) neuropeptide precursor |
| Swissprot | |
| Cellular Localization | Rough endoplasmic reticulum. Cytoplasmic vesicle. Cell junction, synapse. Note: Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. |
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