HDAC8 Polyclonal Antibody (E-AB-14127)
For research use only.
| Verified Samples |
Verified Samples in WB: 293T Verified Samples in IHC: Human tonsil, Human thyroid cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HDAC8 |
| Abbre | HDAC8 |
| Synonyms | CDA07, CDLS5, HD 8, HD8, HDAC 8, HDAC8, HDACL 1, HDACL1, Hdac8, Histone deacetylase 8, Histone deacetylase like 1, MRXS6, RPD 3, RPD3, WTS |
| Swissprot | |
| Calculated MW | 42 kDa |
| Cellular Localization | Nucleus. Cytoplasm. Excluded from the nucleoli. Found in the cytoplasm of cells showing smooth muscle differentiation. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. |
Other Clones
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Other Formats
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Unconjugated
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