For research use only.
| Verified Samples |
Verified Samples in IHC: Human esophagus cancer, Human thyroid cancer |
| Dilution | IHC 1:50-1:300 |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human HIRIP3 |
| Abbre | HIRIP3 |
| Synonyms | HIRA-interacting protein 3, HIRIP3, HIRP3 |
| Swissprot | |
| Cellular Localization | Nucleus. Nuclear throughout the cell cycle and is excluded from condensed chromatin during mitosis. |
| Concentration | 1.02 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Developmental biology, Stem cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Other Clones
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