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For research use only.

Verified Samples Verified Samples in IHC: Human brain, Human thyroid cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human HK2
Synonyms DKFZp686M1669,  HK 2,  HK II,  HK2,  HKII,  HXK2,  Hexokinase 2,  Hexokinase 2 muscle,  Hexokinase type II,  Hexokinase-2,  HxK 2,  HxK2,  Muscle form hexokinase
Swissprot
Cellular Localization Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
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Unconjugated

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