HNF1B Polyclonal Antibody (E-AB-12661)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human lung cancer |
| Dilution | IHC 1:100-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human HNF1B |
| Abbre | HNF1B |
| Synonyms | FJHN, HNF 1B, HNF 2, HNF-1-beta, HNF-1B, HNF1 beta, HNF1 homeobox B, HNF1B, HNF1beta, HNF2, HPC11, Hepatocyte nuclear factor 1 beta, Hepatocyte nuclear factor 1-beta, Homeoprotein LF B3, Homeoprotein LFB3, LF B3, LFB3, MODY 5, MODY5, TCF, TCF 2, TCF 2 protein, TCF-2, TCF2 |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |
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