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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human HSD3B1
Abbre HSD3B1
Synonyms 3BETAHSD,  HSD3B,  HSDB3,  HSDB3A,  I,  SDR11E1
Swissprot
Cellular Localization Endoplasmic reticulum, endoplasmic reticulum membrane, smooth endoplasmic reticulum membrane, Mitochondrion, mitochondrial inner membrane, mitochondrial intermembrane space, Other locations: integral component of membrane.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background HSD3B1 is a human gene that encodes for a 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type I or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1.While it can carry out the same function as HSD3B2, it localizes primarily to different tissues, such as the placenta and nonsteroidogenic tissues.Its requirement for the production of progesterone by the placenta, which has a vital role in pregnancy, may be one reason why no disease based on mutations in this gene has been identified to date.
Other Clones

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Unconjugated

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