HSD3B7 Polyclonal Antibody (E-AB-11311)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human prostate cancer, Human brain |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HSD3B7 |
| Abbre | HSD3B7 |
| Synonyms | 3 beta HSD VII, 3 beta hydroxy Delta(5) C27 steroid oxidoreductase, 3 beta hydroxysteroid dehydrogenase type 7, 3 beta hydroxysteroid dehydrogenase type VII, 7 alpha diol 3 beta dehydrogenase, AI195443, BB098564, C(27) 3 beta HSD, Cca2, Cholest 5 ene 3 beta, Conflu |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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