Human AR Antibody Pair Set (E-KAB-0676)
Add to cart
For research use only.
| Background |
Amphiregulin was initially identified in the conditioned medium of human mammary gland MCF-7 cells treated with TPA. The mouse gene was cloned from the androgen-dependent SC2G cell line derived from Shionogi mouse mammary carcinoma SC115. It belongs to the EGF family of proteins that includes EGF,TGF-α,heparin-binding EGF like-growth factor (HB-EGF),epigen,epiregulin,and betacellulin. Mouse amphiregulin is derived from a 248 amino acid transmembrane precursor and it has 66% identity to the human protein. All the EGF family members are synthesized as type I membrane protein precursors,which can undergo proteolytic cleavage at the plasma membrane to release a mature soluble ectodomain. ADAM17 (TACE) has an important role in ectodomain shedding of amphiregulin,TNF-α,and HB-EGF.
|
| Synonyms |
AREG, CRDGF, SDGF
|
| Swissprot | |
| Reactivity |
Human
|
| Specificity |
Detects Human AR in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
| Introduction |
This ELISA kit applies to the in vitro quantitative determination of Human AR concentrations in serum, plasma and other biological fluids.
|
| Cat.No. | Product Name | Clone No. |
|---|
-
IF：{{item.impact}}
Journal：{{item.journal}} ({{item.year}})
DOI：{{item.doi}}Reactivity：{{item.species}}
Sample Type：{{item.sample_type}}
-
Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}}
