Human CFD Antibody Pair Set (E-KAB-0410)
For research use only.
| Background |
This gene encodes a member of the S1 , or chymotrypsin , family of serine peptidases. This protease catalyzes the cleavage of factor B , the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine , a cell signaling protein secreted by adipocytes , which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency , which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
|
| Synonyms |
ADN, Adipsin, DF, PFD, Factor D, Properdin Factor D Esterase
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| Swissprot | |
| Reactivity |
Human
|
| Specificity |
Detects Human CFD in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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Other Clones
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