Human EGFR Antibody Pair Set (E-KAB-0024)
For research use only.
| Background |
EGFR,also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression,including cell proliferation,apoptosis,angiogenesis,and metastatic spread. Mutations in this gene are associated with lung cancer.
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| Synonyms |
EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA,
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human EGFR in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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