Human GDF15 Antibody Pair Set (E-KAB-0029)
For research use only.
| Background |
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF15 mRNA is most abundant in the liver, with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung.
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| Synonyms |
GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB, Macrophage inhibitory cytokine 1, NSAID-activated gene 1 protein (NAG-1), NSAID-regulated gene 1 protein (NRG-1), Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human GDF15 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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