Human HP Antibody Pair Set (E-KAB-0195)
For research use only.
| Background |
HP(Haptoglobin) is also named as zonulin and belongs to the peptidase S1 family. HP,a plasma glycoprotein that binds free hemoglobin,has a tetrameric structure of 2 alpha(16 kDa and 9 kDa) and 2 beta(40 kDa) polypeptides that are covalently associated by disulfide bonds. In most species,apart from ruminants,Hp has a molecular mass of 100 kDa,consisting of two subunits of 40 kDa and two subunits of 9 kDa,although in a few species,such as man,genetic variant of Hp forms polymers of higher mass. Recent studies of haptoglobin show that certain oligosaccharide structures predominate in different diseases. For example,a highly-fucosylated structure is found in breast cancer and ovarian cancer,highly-sialylated structures in Crohn’s disease and highly branched structures in alcoholic liver disease and fucosylated haptoglobin is a good serum marker for pancreatic cancer..
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| Synonyms |
HP, BP, HP2ALPHA2, HPA1S, Haptoglobin, Zonulin
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human HP in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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