Human HSP-27/HSPB1 Antibody Pair Set (E-KAB-0462)
For research use only.
| Background |
This gene encodes a member of the small heat shock protein ( HSP20 ) family of proteins. In response to environmental stress , the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers , and the encoded protein may promote cancer cell proliferation and metastasis , while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
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| Synonyms |
HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human HSP-27/HSPB1 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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Other Clones
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