Human IL-21 Antibody Pair Set (E-KAB-0483)
For research use only.
| Background |
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells.Implicated in the generation and maintenance of T follicular helper ( Tfh ) cells and the formation of germinal-centers. Together with IL6 , control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection.May play a role in proliferation and maturation of natural killer ( NK ) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells.During T-cell mediated immune response may inhibit dendritic cells ( DC ) activation and maturation.
|
| Synonyms |
IL21, Za11
|
| Swissprot | |
| Reactivity |
Human
|
| Specificity |
Detects Human IL-21 in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
Other Clones
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