Human IL-29 Antibody Pair Set (E-KAB-0232)
For research use only.
| Background |
Cytokine with antiviral,antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense,predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1,and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG),which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
|
| Synonyms |
IL29, ZCYTO21, IFNL1
|
| Swissprot | |
| Reactivity |
Human
|
| Specificity |
Detects Human IL-29 in ELISAs
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| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
| Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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