Human IL-5 Antibody Pair Set (E-KAB-0470)
For research use only.
| Background |
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation , maturation , recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor , which is a heterodimer , whose beta subunit is shared with the receptors for interleukine 3 ( IL3 ) and colony stimulating factor 2 ( CSF2/GM-CSF ) . This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 ( IL4 ) , interleukin 13 ( IL13 ) , and CSF2 . This gene , IL4 , and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
|
| Synonyms |
IL5, EDF, TRF, E-CSF, ESGF
|
| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human IL-5 in ELISAs
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| Applications |
ELISA
|
| Storage |
-20℃
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| Expiration date |
12 months
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Other Clones
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