Human MIP-1β Antibody Pair Set (E-KAB-0269)
For research use only.
| Background |
The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
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| Synonyms |
CCL4, ACT2, AT744.1, G-26, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA4, ACT-2, MIP-1-beta(1-69), C-C motif chemokine 4, chemokine ligand 4, Lymphocyte activation gene 1 protein, Macrophage inflammatory protein 1-beta, MIP1 beta, MIP-1 beta, PAT 744, secreted protein G-26, small inducible cytokine A4, Small-inducible cytokine A4, T-cell activation protein 2
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human MIP-1β in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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