Human MMP-7 Antibody Pair Set (E-KAB-0501)
For research use only.
Background |
Proteins of the matrix metalloproteinase ( MMP ) family are involved in the breakdown of extracellular matrix in normal physiological processes , such as embryonic development , reproduction , and tissue remodeling , as well as in disease processes , such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans , fibronectin , elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing , and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
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Synonyms |
MMP7, MPSL1, PUMP-1, Matrilysin
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Swissprot | |
Reactivity |
Human
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Specificity |
Detects Human MMP-7 in ELISAs
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Applications |
ELISA
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Storage |
-20℃
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Expiration date |
12 months
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Other Clones
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