Human NEFL Antibody Pair Set (E-KAB-0485)
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For research use only.
| Background |
Neurofilaments are type IV intermediate filament heteropolymers composed of light , medium , and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F ( CMT1F ) and 2E ( CMT2E ) , disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
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| Synonyms |
68 kDa neurofilament
protein, CMT1F, CMT2E, CMTDIG, Light
polypeptide, NF-L, NF68, NFL, Neurofilament, Neurofilament lightpolypeptide, Neurofilament triplet Lprotein, Neurofilamentlight, PPP1R11
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human NEFL in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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