Human RANTES Antibody Pair Set (E-KAB-0206)

For research use only.
Background |
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
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Synonyms |
CCL5, D17S136E, SCYA5
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Swissprot | |
Reactivity |
Human
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Specificity |
Detects Human RANTES in ELISAs
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Applications |
ELISA
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Storage |
-20℃
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Expiration date |
12 months
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Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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Other Clones
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