Human tPA Antibody Pair Set (E-KAB-0273)
For research use only.
| Background |
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
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| Synonyms |
PLAT, T-PA, TPA
|
| Swissprot | |
| Reactivity |
Human
|
| Specificity |
Detects Human tPA in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
|
| Expiration date |
12 months
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| Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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