Human TSLP Antibody Pair Set (E-KAB-0471)
For research use only.
Background |
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c ( + ) dendritic cells. The protein promotes T helper type 2 ( TH2 ) cell responses that are associated with immunity in various inflammatory diseases , including asthma , allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
|
Synonyms |
TSLP
|
Swissprot | |
Reactivity |
Human
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Specificity |
Detects Human TSLP in ELISAs
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Applications |
ELISA
|
Storage |
-20℃
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Expiration date |
12 months
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Other Clones
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