Human TSLP Antibody Pair Set (E-KAB-0471)
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For research use only.
| Background |
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c ( + ) dendritic cells. The protein promotes T helper type 2 ( TH2 ) cell responses that are associated with immunity in various inflammatory diseases , including asthma , allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
|
| Synonyms |
TSLP
|
| Swissprot | |
| Reactivity |
Human
|
| Specificity |
Detects Human TSLP in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
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