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For research use only.

Verified Samples Verified Samples in IHC: Human renal cancer, Human ovarian cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human HYAL2
Abbre HYAL2
Synonyms HYAL2,  Hyal 2,  Hyal-2,  Hyal2,  Hyaluronidase 2,  Hyaluronidase 2 Precursor,  Hyaluronidase-2,  Hyaluronoglucosaminidase 2,  Hyaluronoglucosaminidase-2,  LUCA 2,  LUCA-2,  LUCA2,  Lung carcinoma protein 2,  PH 20 homolog,  PH-20 homolog,  PH20 homolog,  lysosomal hyaluronidase
Swissprot
Cellular Localization Cell membrane.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
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Unconjugated

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