HYAL3 Polyclonal Antibody (E-AB-15117)
For research use only.
| Verified Samples |
Verified Samples in WB: Human kidney Verified Samples in IHC: Human cervical cancer, Human prostate cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HYAL3 |
| Abbre | HYAL3 |
| Synonyms | HYAL3, Hyal-3, Hyaluronidase 3, Hyaluronidase-3, Hyaluronoglucosaminidase 3, Hyaluronoglucosaminidase-3, LUCA-3, LUCA14, LUCA3, Lung carcinoma protein 3, Minna14 |
| Swissprot | |
| Calculated MW | 47 kDa |
| Cellular Localization | Secreted. Lysosome. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. |
Other Clones
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Other Formats
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Unconjugated
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