IFT57 Polyclonal Antibody (E-AB-52949)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil |
| Dilution | IHC 1:50-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human IFT57 |
| Abbre | IFT57 |
| Synonyms | CDNA FLJ10147 fis clone HEMBA1003369, DERP 8, DERP8, Dermal papilla derived protein 8, Dermal papilla-derived protein 8, ESRRBL1 protein, Esrrbl 1, Esrrbl1, Estrogen related receptor beta like 1, Estrogen related receptor beta like protein 1, Estrogen-related recep |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton>cilium basal body. Concentrates within the inner segment of cilia. |
| Concentration | 1.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
Other Clones
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Other Formats
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Unconjugated
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