IL-1 beta/IL1B Monoclonal Antibody (AN200015P)
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For research use only.
| Verified Samples | Verified Samples in IHC: Human lung, Human liver |
| Dilution | IHC-P 1:100-1:500, |
| Isotype | Mouse IgG1 |
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human IL-1 beta / IL1B Protein |
| Abbre | IL1B |
| Synonyms | catabolin, IL 1B, IL-1, IL-1 beta, IL-1B, IL-1F, IL-1F2, IL1 beta, IL1-BETA, IL1B, IL1F, IL1F2, pro Catabolin, pro IL1B, pro IL1F, pro IL1F2, pro leukocytic endogenous mediator, pro leukocytic pyrogen, pro lymphocyte activating factor, pro mononuclear cell factor |
| Swissprot | |
| Cellular Localization | Cytoplasm, Cytosol, Secreted, Lysosome, Secreted, Extracellular exosome. |
| Tissue Specificity | Monocytes/macrophages. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Immunology, Cardiovascular, Metabolism |
| Clone | A859 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. |
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