IL10RA Polyclonal Antibody (E-AB-10098)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human lung cancer, Human tonsil |
| Dilution | IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human IL10RA |
| Abbre | IL10RA |
| Synonyms | IL-10R subunit, Interleukin-10 receptor subunit, IL-10R, IL10RA, CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R, IL-10 receptor subunit alpha, IL-10R subunit 1, IL-10R subunit alpha, IL-10RA, Interleukin-10 receptor subunit 1, Interleukin-10 receptor subunit alpha, IL-10R1, IL-10Ra, CDw210a antigen, HIL 10R, HIL10R, I10R1, IL 10R, IL 10R 1, IL 10R A, IL 10R1, IL10R1, Interleukin 10 receptor alpha, Interleukin 10 receptor alpha chain |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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