IL4R Polyclonal Antibody (E-AB-52020)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human tonsil |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human IL4R |
| Abbre | IL4R |
| Synonyms | 582J, IL4R, CD124, IL-4RA, IL4RA, IL-4 receptor subunit alpha, IL-4-binding protein, IL4-BP, IL-4R subunit alpha, IL-4R-alpha, Interleukin-4 receptor subunit alpha, 582J2.1, IL-4R&, alpha, IL 4R alpha, IL4R nirs variant 1, IL4RA, Interleukin 4 receptor, Interleukin 4 receptor alpha chain, sIL4Ralpha/prot, Soluble IL-4 receptor subunit alpha, Soluble IL-4R-alpha, Soluble interleukin-4 receptor subunit alpha |
| Swissprot | |
| Cellular Localization | Secreted and Cell membrane. |
| Concentration | 1.26 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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