IMPDH2 Polyclonal Antibody (E-AB-11330)
For research use only.
| Verified Samples |
Verified Samples in WB: A549 Verified Samples in IHC: Human lung cancer, Human liver cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human IMPDH2 |
| Abbre | IMPDH2 |
| Synonyms | IMDH2, IMP (inosine monophosphate) dehydrogenase 2, IMP dehydrogenase 2, IMP oxireductase 2, IMPD 2, IMPD2, IMPDH 2, IMPDH II, IMPDH-II, Impdh2, Inosine 5' monophosphate dehydrogenase 2, Inosine 5' phosphate dehydrogenase 2, Inosine monophosphate dehydrogenase type I |
| Swissprot | |
| Calculated MW | 56 kDa |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome, extracellular region, Nucleus, Peroxisome, peroxisomal membrane, Other locations: cytoplasm, ficolin-1-rich granule lumen, membrane, secretory granule lumen. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
Other Clones
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Other Formats
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Unconjugated
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