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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human gastric cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human IRAK4
Abbre IRAK4
Synonyms IL-1 receptor-associated kinase 4,  IPD1,  IRAK 4,  IRAK-4,  IRAK4,  IRAK4 mutated form 1,  Interleukin 1 receptor associated kinase 4 mutant form 1,  Interleukin-1 receptor-associated kinase 4,  Interleukin1 receptor associated kinase 4,  LOC 51135,  NY REN ,  NY REN 64
Swissprot
Cellular Localization Cytosol, Endosome membrane, Extracellular region or secreted, extracellular space, Nucleus, Plasma Membrane, Other locations: cytoplasm.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Immunology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Clones

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Unconjugated

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