ITGA2B Polyclonal Antibody (E-AB-15138)

For research use only.
Verified Samples |
Verified Samples in WB: Human placenta, Human fetal liver |
Dilution | WB 1:500-1:2000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | WB |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human ITGA2B |
Abbre | ITGA2B |
Synonyms | BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GPalpha IIb, GT, GTA, HPA3, ITA2B, ITGAB, Integrin, Integrin alpha 2b, Integrin alpha IIb, Integrin alpha-IIb light chain, Itga2b, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41, antigen CD41), form 2, platelet |
Swissprot | |
Calculated MW | 113 kDa |
Cellular Localization | Membrane. |
Concentration | 0.5 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Immunology, Signal Transduction, Stem Cells |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. |
Other Clones
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Other Formats
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Unconjugated
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