ITGA3 Polyclonal Antibody (E-AB-18119)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human tonsil |
| Dilution | IHC 1:40-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ITGA3 |
| Abbre | ITGA3 |
| Synonyms | AA407068, Antigen identified by monoclonal J143, CD49 antigen like family member C, CD49 antigen-like family member C, CD49c, CD49c antigen, FLJ34631, FLJ34704, FRP 2, FRP-2, FRP2, GAP B3, GAPB3, Galactoprotein B3, Integrin, Integrin alpha 3, Integrin alpha-3 light chain |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 1.32 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | ITGA3,also named as MSK18,CD49c,GAPB3 and FRP-2,belongs to the integrin alpha chain family. It is a receptor for fibronectin,laminin,collagen,epiligrin,thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain(840aa) and light chain(176aa). This antibody can recognize the heavy chain. |
Other Clones
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Other Formats
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Unconjugated
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