KCNA1 Polyclonal Antibody (E-AB-66980)
                        For research use only.
| Verified Samples | 
                                Verified Samples in IF: Mouse brain | 
        
| Dilution | IF 1:50-1:200 | 
| Isotype | IgG | 
| Host | Rabbit | 
| Reactivity | Mouse, Rat | 
| Applications | IF | 
| Clonality | Polyclonal | 
| Immunogen | Recombinant fusion protein of human KCNA1 (NP_000208.2). | 
| Abbre | KCNA1 | 
| Synonyms | AEMK, EA1, HBK1, HUK1, KCNA1, KV1.1, MBK1, MK1, RBK1 | 
| Swissprot | |
| Cellular Localization | Membrane. | 
| Concentration | 1 mg/mL | 
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. | 
| Purification Method | Affinity purification | 
| Research Areas | Cancer, Neuroscience | 
| Conjugation | Unconjugated | 
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. | 
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. | 
| background | This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). | 
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