Ki67/MKI67 Monoclonal Antibody (AN200153P)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human small intestine, Human liver Verified Samples in IF: Hela |
| Dilution | IHC-P 1:500-1:2000, ICC/IF 1:20-1:100 |
| Isotype | IgG2b |
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P, ICC/IF |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide corresponding to the center region of the Human Ki67/MKI67 |
| Abbre | MKI67 |
| Synonyms | MIB, MKI, marker of proliferation Ki, Proliferation marker protein Ki, Antigen identified by monoclonal antibody Ki, PPP1R, MKI67, KIA, MIB-, MIB-1, PPP1R105, marker of proliferation Ki-67, Ki67, Antigen identified by monoclonal antibody Ki-67, Antigen Ki67, Antigen KI-67, Proliferation marker protein Ki-67, Antigen identified by monoclonal Ki 67, Antigen identified by monoclonal Ki-67, MIB 1, Proliferation related Ki 67 antigen, Protein phosphatase 1 regulatory subunit 105, RP11-380J17.2 |
| Swissprot | |
| Cellular Localization | Nucleus |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Cell Biology, Neuroscience, Tags & Cell Markers, Cancer |
| Clone No. | 1A8 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization. It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). |
Other Clones
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Other Formats
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Unconjugated
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