KIF3A Polyclonal Antibody (E-AB-10420)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse brain, Human fetal brain, Human brain malignant glioma |
| Dilution | WB 1:200-1:1000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human KIF3A |
| Abbre | KIF3A |
| Synonyms | KIF 3, KIF 3A, KIF3, KIF3A, Kif3a, Kifl, Kinesin family member 3A, Kinesin family protein 3, Kinesin family protein 3A, Kinesin like protein KIF 3A, Kinesin like protein KIF3A, Kinesin-like protein KIF3A, Kns3, Microtubul, Microtubule plus end directed kinesin motor 3A |
| Swissprot | |
| Calculated MW | 80 kDa |
| Cellular Localization | Cytoplasm>cytoskeleton. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene.Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C.KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis.KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined.Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate. |
Other Clones
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Other Formats
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Unconjugated
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