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For research use only.

Verified Samples Verified Samples in IHC: Human esophagus cancer, Human brain
Dilution IHC 1:50-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human KLF1
Abbre KLF1
Synonyms CDAN4,  EKLF,  EKLF PEN,  Erythroid Kruppel like factor,  Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor),  Erythroid krueppel-like transcription factor,  Erythroid specific transcription factor EKLF,  HBFQTL6,  Human erythroid-specif
Swissprot
Cellular Localization Nucleus. Colocalizes with SUMO1 in nuclear speckles.
Concentration 0.96 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.
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Unconjugated

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